Spikes can be taken as absolute quantities of measuring values which are large than approximately four (expressed as variable [Times_SD] in the program)times of the standard deviation of the time series, and can be removed by repeating 3 times with each time series. When a measuring value with the deviation from the mean larger than four times of the standard deviation, the variable can be taken as NO_VALUE, and the number of spikes is saved into the variable [SpikeNum]. If the variable [Times_SD] is taken as four, many records will be removed, so the variable [Times_SD] can be taken as larger, for example eight.