This manual describes how to run the Matlab® Artificial Immune Systems tutorial presentation developed by Leandro de Castro and Fernando Von Zuben. The program files can be downloaded from the following FTP address: ftp://ftp.dca.fee.unicamp.br/pub/docs/vonzuben/lnunes/demo.zip The tour is self-guided and can be performed in any order. To run the presentation, first uncompress the zipped archive and store it in an appropriate directory. Run the Matlab® , enter the selected directory, and type “tutorial” in the prompt.